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In this study recently published in the New England Journal of Medicine, the authors conducted a phase 1, dose-escalation, open-label trial including 45 healthy adults, 18 to 55 years of age, who received two vaccinations, 28 days apart, with candidate vaccine mRNA-1273 (which encodes the stabilised prefusion SARS-CoV-2 spike protein) in a dose of 25 μg, 100 μg, or 250 μg.

In this controlled, open-label trial recently published in the New England Journal of Medicine, the authors randomly assigned patients who were hospitalised with COVID-19 to receive either oral or intravenous dexamethasone (at a dose of 6 mg once daily) for up to 10 days or usual care.

In this paper, just published in the New England Journal of Medicine, the authors report neuropathological findings from autopsies of 18 consecutive patients with SARS-CoV-2 infection who died in a single teaching hospital between April 14 and April 29, 2020.

This retrospective multicentre study aimed to assess the number of patients with acute ischaemic cerebrovascular events seeking inpatient medical emergency care since the implementation of social distancing measures during the COVID-19 pandemic.

In this paper recently published in Neurology, the authors aimed to determine whether neurological manifestations are common in hospitalised COVID-19 patients and to describe their main characteristics.

In this study, recently published in Neurology Neuroimmunology & Neuroinflammation, the authors conducted a survey on the risk of COVID-19 in patients with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD).

In this paper, the authors report a case of Guillain-Barré syndrome (GBS) with onset 2 weeks after SARS-CoV-2 infection and highly elevated serum antibodies against SARS-CoV-2, supporting an association between SARS-CoV-2 disease and GBS.

In this prospective observational cohort study with rapid data gathering and near real-time analysis, the authors characterised the clinical features of patients admitted to hospital with Covid-19 in the United Kingdom during the growth phase of the first wave of the outbreak. Patients were enrolled in the International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) World Health Organisation (WHO) Clinical Characterisation Protocol UK (CCP-UK) study, and risk factors associated with mortality in hospital were explored.

Immunosuppression and immunomodulation are valuable therapeutic approaches for managing neuroimmunological diseases. In the present COVID-19 pandemic, clinicians must deal with the question of whether immunotherapy should currently be initiated or discontinued in neurological patients.

In this paper, the authors systematically analysed lung tissue samples from 38 patients who died from COVID-19 in two hospitals in northern Italy between Feb 29 and March 24 2020.

In this paper, just published in Lancet, the authors performed a dose-escalation, single-centre, open-label, non-randomised, phase 1 trial of a recombinant adenovirus type-5 (Ad5) vectored COVID-19 vaccine in Wuhan, China.

In this paper, the authors investigated the effects of physical distance, face masks, and eye protection on virus transmission in healthcare and non-healthcare settings.

In this paper just published in the New England Journal of Medicine, the authors report the natural history of asymptomatic SARS-CoV-2 infection from part of the cohort of the 410 infected people on the cruise ship, Diamond Princess, who were asymptomatic at the time of testing.

In this paper, the authors conducted a prospective national-level data collection of patients treated with mechanical thrombectomy (MT), across 45 days of pandemic containment measures, compared to patients treated during the same calendar period in 2019.

On June 3, we published in the Breaking News section of this site the article entitled “Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis” previously published in Lancet. On June 13, the article was retracted by three of the four authors.