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In this study, recently published in the New England Journal of Medicine, the authors report the neurologic features in an observational series of 58 of 64 consecutive patients admitted to two intensive care units (ICUs) in Strasbourg, France, because of… Continue Reading

Anna Bersano and Natan Bornstein on behalf of EAN Stroke Management Panel According to the WHO, the spread of coronavirus disease 2019 (COVID-19) has already reached pandemic proportion, affecting at present more than 2.034.000 patients worldwide. Although the majority of… Continue Reading

The ongoing COVID-19 outbreak raises new management challenges, which lack an evidence-based answer to date. The management group of the EAN Scientific Panel for Autonomic Nervous System (ANS) Disorders discusses below some management aspects relevant to patients with autonomic disorders.… Continue Reading

COVID-19 AND NEUROLOGY In this useful consensus paper, the current clinical guidelines and research progress on the management of COVID-19 are summarized, emphasizing on its neurological manifestations.  The aim of consensus was to help neurologists to understand the occurrence, development… Continue Reading

COVID-19 AND NEUROLOGY During the COVID-19 outbreak, frontline healthcare workers were mandated to wear personal protective equipment (PPE) while caring for suspected or confirmed COVID-19 patients, which involved the donning of face masks, protective eyewear, gowns, surgical gloves and the… Continue Reading

COVID-19 AND NEUROLOGY Because most patients with MG are on immunosuppressive or immunomodulatory therapies and may also have respiratory muscle weakness, there is a theoretical concern that MG/LEMS patients may be at higher risk of contracting the infection or experiencing… Continue Reading

COVID-19 AND NEUROLOGY The aim of this multicenter study was to investigate and characterize the occurrence of olfactory and gustatory disorders in patients with laboratory-confirmed COVID-19 infection. A total of 417 mild-to-moderate COVID-19 patients were included in the study; in… Continue Reading

COVID-19 TREATMENT In this report, the authors describe outcomes in a cohort of patients hospitalized for severe Covid-19 who were treated with remdesivir on a compassionate-use basis. Remdesivir is a prodrug of a nucleotide analogue that is intracellularly metabolized to… Continue Reading

COVID-19 TREATMENT In this nice narrative review just published in JAMA, the authors summarize current evidence regarding major proposed treatments, repurposed or experimental, for COVID-19 and provides a summary of current clinical experience and treatment guidance for this novel epidemic… Continue Reading

Helbok R, Öztürk S On behalf of the Members of the EAN Scientific Panel Neurocritical care Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe disease are commonly admitted… Continue Reading

My name is Rita and I am a 4th year Neurology resident in a peripheral hospital of northern Portugal, which is located near one of the first COVID-19 pandemic outbreaks in Portugal, the city of Ovar. Although the first case… Continue Reading

In this correspondence, Zhao et al. report the first case of COVID-19 initially presenting with acute Guillain-Barré syndrome (GBS) suggesting a possible association between GBS and SARS-CoV-2 infection. The authors assumed that GBS associated with SARS-CoV-2 might follow the pattern… Continue Reading

In a case series of 214 patients with coronavirus disease 2019 (COVID-19) Mao et al., report that neurologic symptoms were seen in 36.4% of patients and were more common in patients with severe infection (45.5%) according to their respiratory status.… Continue Reading

In this brief report, Poyiadji et al. describe the first presumptive case of COVID-19–associated acute necrotizing encephalopathy (ANE) in a 50-year-old female patient who presented with a 3-day history of cough, fever, and altered mental status. Brain MRI demonstrated haemorrhagic… Continue Reading

This paper addresses the possible proposed neurotropic mechanisms of COVID-19 virus and its analogies and differences with SARS-CoV virus. Indeed, similar to SARS-CoV, COVID-19 virus exploits the angiotensin-converting enzyme 2 (ACE2) receptor to gain entry inside the cells. In particular,… Continue Reading