Each month the EANpages editorial team reviews the scientific press for recently published papers of outstanding interest to neurologists. Here we present our selection for April 2023.
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Research Highlights
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Each month the EANpages editorial team reviews the scientific press for recently published papers of outstanding interest to neurologists. Here we present our selection for March 2023.
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Research Highlights
Performance of the 2017 and 2010 Revised McDonald Criteria in Predicting MS Diagnosis After a Clinically Isolated Syndrome – A MAGNIMS Study
September 26, 2022The 2017 McDonald criteria showed higher sensitivity, lower specificity, and similar accuracy in predicting clinically definite multiple sclerosis compared to 2010 McDonald criteria, while shortening time to its diagnosis. -
Research Highlights
Relapse-independent disability worsening plays a relevant role in every disease phase of MS
September 26, 2022Insidious disability accrual starts already in the earliest phases of multiple sclerosis and becomes dominant over the disease course, suggesting an ongoing process of inflammation and/or degeneration secondary to disease burden. -
Research Highlights
Epstein-Barr virus infection is a major risk factor for the development of multiple sclerosis
September 26, 2022Epstein-Barr virus infection is the strongest known risk factor for the development of multiple sclerosis, and it precedes preclinical manifestation of the disease suggesting a possible causal role -
Research Highlights
Glymphatic system impairment may contribute to multiple sclerosis pathology
September 23, 2022In multiple sclerosis, an impairment of the glymphatic system may contribute to pathology accrual in the central nervous system and disability progression. -
Research Highlights
Characterizing amyloid-positive individuals with persistent normal tau PET levels
September 23, 2022Baseline characteristics of Aβ-positive individuals can help identify those who will remain tau-negative for at least 5 years. -
Greater diffusion restriction in the white matter of amyloid-beta-positive cognitively unimpaired individuals supports the role of inflammation in early preclinical AD.
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Research Highlights
Effect of Intra-arterial Alteplase after Angiographically Successful Thrombectomy
September 23, 2022New Neurology Update from Stroke Scientific Panel -
The revised Boston criteria allow for a more accurate diagnosis of cerebral amyloid angiopathy
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Research Highlights
Whole genome sequencing for the diagnosis of neurological repeat expansion disorders
September 23, 2022WGS can reliably assess the most common neurological disease-causing repeat expansions, further supporting its implementation in clinical practice. -
Research Highlights
How does palliative care help people with neurological disease and their caregivers?
September 23, 2022New Neurology Update from Palliative Care is in! Read more about the topics here -
Palliative care outpatient clinics, with a multidisciplinary team, helps patients with Parkinson’s disease and related disorders and their families.
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Event Related Potentials might be an accurate neurophysiological biomarker for early diagnosis of AD and prediction of MCI to AD conversion.
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Research HighlightsResearch
Progressive multifocal leukoencephalopathy – promising therapeutic approach with allogeneic BK virus-specific T cells
May 17, 2021Two patients with severe PML have been successfully treated with BK virus-specific T cells at Hannover Medical School's Department of Neurology, according to director, Prof. Günter Höglinger.