Paper of the Month

Our research paper of the month is a pooled retrospective non-randomised cohort study, evaluating the functional and safety outcomes of direct to angiography (DTA) treatment paradigm vs repeated imagingin the different treatment windows and on-call hours vs regular hours in patients undergoing thrombectomy.

For August 2021, we have selected two COVID-19 papers of the month, investigating the effectiveness of the Covid-19 vaccines in England and Israel, respectively.

For July 2021, we have selected: Langezaal LCM et al. Endovascular Therapy for Stroke Due to Basilar-Artery Occlusion. N Engl J Med 2021; 384:1910-1920. DOI: 10.1056/NEJMoa2030297

For July 2021, we have selected: Greinacher A. et al, Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination. N Engl J Med. 2021 Jun 3;384(22):2092-2101. doi: 10.1056/NEJMoa2104840.

For May 2021, we have selected: Walgaard et al. Second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial. Lancet Neurol 2021; 20=:275-283. doi: 10.1016/S1474-4422(20)30494-4.

For June 2021, we have selected the following paper: Dagan N. et al. BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting. N Engl J Med 2021; 384:1412-1423. doi: 10.1056/NEJMoa2101765.

For May 2021, we have selected: Rentsch CT et al. Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study. BMJ 202;372:n311. doi: 10.1136/bmj.n311.

For May 2021, we have selected: Walgaard et al. Second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial. Lancet Neurol 2021; 20=:275-283. doi: 10.1016/S1474-4422(20)30494-4.

Paper of the month: Association Between Dispatch of Mobile Stroke Units and Functional Outcomes Among Patients With Acute Ischemic Stroke in Berlin

For April 2021, we have selected: Pun B.T. et al. Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study. Lancet Respir Med. 2021; 9:239-250. doi: 10.1016/S2213-2600(20)30552-X.

For March 2021, we have selected: Krienke C. et al., A non-inflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis. Science 2021; 371: 145-153. doi: 10.1126/science.aay3638.

For March 2021, we have selected: Lynch D.R. et al. Safety and Efficacy of Omaveloxolone in Friedreich Ataxia (MOXIe Study). Ann Neurol 2021; 89:212-225. doi: 10.1002/ana.25934.

For February 2020, we have selected: Polack F.P. et al. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

For February 2020, we have selected: Hutchinson P.J. et al. Trial of Dexamethasone for Chronic Subdural Hematoma. N Engl J Med. 2020. PMID: 33326713 Clinical Trial.

For January 2021, we have selected: Matschke et al. Neuropathology of patients with COVID-19 in Germany: a post-mortem case series. Lancet Neurol 2020; 19:919-929. doi: 10.1016/S1474-4422(20)30308-2.