Research

This Symposium on ‘Early detection and treatment of Parkinson’s disease’ was organised in co-operation with the International Parkinson and Movement Disorder Society – European Section.

This interesting joint session with the European Association of Neuro-Oncology (EANO) provided a picture of biomarkers in Neuro-Oncology including imaging, biological and clinical features.

The RRFS Special Session on Unveiling research in Neurology was among the first events at EAN 2022, providing residents and students with examples and suggestions of different aspects of research in neurology.

In this population-based study, the authors aimed to investigate whether increased life expectancy determined by the adherence to a healthy lifestyle has an impact on the overall years lived with AD across the lifespan.

To evaluate the association of COVID-19 infection with olfactory bulb, our authors of the month conducted this multicenter postmortem cohort study, using ultrastructural and histopathological analysis.

Our authors of the month evaluated an experimental treatment for human prion disease, based on a fully humanised monoclonal antibody (PRN100) addressed against the cellular prion protein (PrP).

Our authors of the month conducted this retrospective case-control study in order to investigate the association of AD with the risk of COVID-19 infection (adjusted for comorbidities and sociodemographic factors).

The European Academy of Neurology (EAN) is proposing a new study on the topic of sleep & wake disorders, inspired by the European Brain Council's Value of Treatment projects

Our paper of the month describes a study led by Stanford University researchers, which now provides a mechanistic basis for how EBV infection can trigger the patient’s immune cells to attack self-tissue within the CNS.

Our authors of the month conducted a longitudinal, multi-modal brain imaging study using the UK biobank, whereby participants had already been scanned before getting infected with SARS-CoV-2, offering a unique resource to elucidate these questions.

Our authors of the month conducted a systematic retrospective analysis of 150 lumbar punctures in 127 patients with PCR-proven COVID-19 and neurological symptoms seen at 17 European university centres.

Our research paper of the month for March is a cohort study exploring the risk of developing multiple sclerosis (MS) after infection with Epstein-Barr virus (EBV).

The EU-funded European Brain Research Area project today releases its long-awaited European Research Inventory and Mapping Report.

Our authors of the month conducted a systematic review and meta-analysis in order to summarise the frequency of neurologic manifestations in patients with COVID-19 and to investigate the association of these manifestations with disease severity and mortality.

For February we have selected Safety and efficacy of once-daily risdiplam in type 2 and non-ambulant type 3 spinal muscular atrophy (SUNFISH part 2): a phase 3, double-blind, randomized, placebo-controlled trial.