In this trial, nonhospitalized patients with symptomatic COVID-19 (≤5 days after the onset of symptoms) and at least one risk factor for disease progression received a single infusion of sotrovimab at a dose of 500 mg or placebo.
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Breaking newsCOVID-19
Humoral immune response in multiple sclerosis patients following PfizerBNT162b2 COVID19 vaccination: Up to 6 months cross-sectional study
November 8, 2021In a prospective cross-sectional study, the authors determined SARS-COV-2 IgG response up to 6 months following PfizerBNT162b2 vaccination in 414 multiple sclerosis (MS) patients and 89 healthy subjects. -
Breaking newsCOVID-19
Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape
September 7, 2021In this article, the authors provide a snapshot of ongoing vaccine efficacy studies, as well as real-world data on vaccine effectiveness and the impact of virus variants of concern. -
Breaking newsCOVID-19
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
September 7, 2021The authors analyse antibodies and T cells of a recently vaccinated, UK cohort, alongside those recovering from natural infection in early 2020. -
Breaking newsCOVID-19
Associations of BNT162b2 vaccination with SARS-CoV-2 infection and hospital admission and death with COVID-19 in nursing homes and healthcare workers in Catalonia: prospective cohort study
September 7, 2021The objective of this prospective cohort study was to determine associations of BNT162b2 vaccination with SARS-CoV-2 infection and hospital admission and death with COVID-19 among nursing home residents, nursing home staff, and healthcare workers. -
Breaking newsCOVID-19
Effectiveness of BNT162b2 and mRNA-1273 COVID-19 vaccines against symptomatic SARS-CoV-2 infection and severe COVID-19 outcomes in Ontario, Canada: test negative design study
September 7, 2021The objective of this test negative design study was to estimate the effectiveness of mRNA COVID-19 vaccines against symptomatic infection and severe outcomes (hospital admission or death). -
Breaking newsCOVID-19
Risk of acute myocardial infarction and ischaemic stroke following COVID-19 in Sweden: a self-controlled case series and matched cohort study
September 7, 2021In this article the authors aimed to quantify the risk of acute myocardial infarction and ischaemic stroke associated with COVID-19 by analysing all COVID-19 cases in Sweden. -
Breaking newsCOVID-19
Cerebral venous thrombosis and portal vein thrombosis: A retrospective cohort study of 537,913 COVID-19 cases
September 7, 2021Using a retrospective cohort study based on electronic health records primarily in the USA, the absolute risks of cerebral and portal vein thrombosis in the two weeks following a diagnosis of COVID-19 were calculated. -
Breaking newsCOVID-19
The effect of COVID-19 isolation measures on the cognition and mental health of people living with dementia: A rapid systematic review of one year of quantitative evidence
September 7, 2021This study aimed to summarize the global research evidence describing the effect of COVID-19 isolation measures on the health of people living with dementia. -
Breaking newsCOVID-19
Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial
September 7, 2021The authors of this study report the safety and immunogenicity of heterologous schedules with the ChAd and BNT vaccines. -
Breaking newsCOVID-19
Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study
September 7, 2021For this multicentre cohort study, clinicians were asked to submit all cases in which COVID-19 vaccination preceded the onset of cerebral venous thrombosis, regardless of the type of vaccine, interval between vaccine and onset of cerebral venous thrombosis symptoms, or blood test results. -
Breaking newsCOVID-19
Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial
September 7, 2021In this study the authors aimed to establish whether inhaled budesonide reduces time to recovery and COVID-19-related hospital admissions or deaths among people at high risk of complications in the community. -
Breaking newsCOVID-19
Bell’s palsy following vaccination with mRNA (BNT162b2) and inactivated (CoronaVac) SARS-CoV-2 vaccines: a case series and nested case-control study
September 7, 2021Cross-sectional case-control studies (Blue) Bell’s palsy is a rare adverse event reported in clinical trials of COVID-19 vaccines. However, no population-based study has assessed the association between the inactivated SARS-CoV-2 vaccines and Bell’s palsy. The aim of this study was… Continue Reading -
Breaking newsCOVID-19
Systemic thrombolysis in ischaemic stroke patients with COVID-19
September 6, 2021Observational, retrospective study of 70 patients with AIS, including 22 subjects with evidence of acute COVID-19 infection, consecutively treated with IVT in 4 stroke centres between 15 September and 30 November 2020. -
Breaking newsCOVID-19
Sensory Guillain-Barre syndrome following the ChAdOx1 nCov-19 vaccine: Report of two cases and review of literature
September 6, 2021In this article the authors describe two patients who developed sensory Guillain-Barre syndrome (GBS) shortly after the first dose of the ChAdOx1 vaccine.
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