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Our research paper of the month is an open-label, single-arm, phase II futility trial exploring the safety and the effect of treatment with the antimalarial drug hydroxychloroquine on disability worsening in patients with primary progressive multiple sclerosis.

Our authors of the month conducted a randomised, placebo-controlled, observer-blinded, multinational study to assess the safety, efficacy and immunogenicity of the BNT162b2 vaccine.

EAN President, Claudio Bassetti provides a general update and insights into the EAN’s current activities and priorities.

Our research paper of the month is a retrospective cohort study, aiming to investigate the association between field position, professional career length and playing era and increased risk of neurodegenerative disease among male former professional soccer players.

The aim of this study was to describe neurological and psychiatric complications of infection with SARS CoV 2 in children and adolescents and determine the prevalence of such manifestations in hospitalised patients under 18 years-old.

EAN Secretary General, Elena Moro, provides an update on membership-related issues, including a range of new benefits for EAN members.

For October 2021, we have selected: Spelman T. el al Treatment Escalation vs Immediate Initiation of Highly Effective Treatment for Patients With Relapsing-Remitting Multiple Sclerosis: Data From 2 Different National Strategies.

For October 2021, we have selected: Lopez Bernal J. et al, Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant: test-negative case–control study.

EAN Scientific Committee Chair, Thomas Berger, gives early notice of the upcoming elections for Scientific Panel Management Groups and an update on recent scientific activities.

For September 2021, we have selected: Ramsden CE et al. Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial

For September 2021, we have selected: ''Aschman A et al. Association Between SARS-CoV-2 Infection and Immune-Mediated Myopathy in Patients Who Have Died'' and ''Suh J et al. Skeletal Muscle and Peripheral Nerve Histopathology in COVID-19''

This year has so far been a busy one for everyone involved in education at EAN, with plenty of exciting new projects joining the traditional fixtures in our education calendar. As Chair of the EAN Education Committee, it is my pleasure to give you a brief update on some of our recent activities and to remind you about our brand new programmes with deadlines still open.

Our research paper of the month is a pooled retrospective non-randomised cohort study, evaluating the functional and safety outcomes of direct to angiography (DTA) treatment paradigm vs repeated imagingin the different treatment windows and on-call hours vs regular hours in patients undergoing thrombectomy.

For August 2021, we have selected two COVID-19 papers of the month, investigating the effectiveness of the Covid-19 vaccines in England and Israel, respectively.

I am happy to be writing to you today about our EAN 2021 Virtual Congress, which was a great positive in what continues to be a challenging time.