EAN Congress newsEAN News
				
				
			EAN Virtual Congress: Symposium 4 – Promoting structural repair and functional recovery in multiple sclerosis
				Prof. Centonze presented the first lecture on the subject of the pathophysiological basis of functional recovery in multiple sclerosis, starting with a discussion on the key role played by synaptic plasticity in recovery of function. He presented convincing data obtained by means of transcranial magnetic stimulation indicating that synaptic plasticity reserve prevents clinical disability in patients with multiple sclerosis, and that rehabilitation favours synaptic remodeling and plasticity. In the second part of his lecture, Prof Centonze demonstrated the relevant role of the activation of NMDA, cannabinoid, and dopamine receptors, and of neurotrophins in modulating synaptic plasticity to clinically compensate tissue damage in multiple sclerosis. As a result, treatments aimed at activating these receptors such as D-aspartate, phytocannabinoids, or L-dopa, may have the potential to enhance the beneficial effects of rehabilitation by favouring synaptic plasticity.			
					
				
				
				
				
				
				
				
				
				
				
The Scientific
Panel on Movement Disorders Management Group invites you to join us for the
excellent Movement Disorders program at the EAN Virtual
Congress.  The program has been prepared in collaboration between the
EAN and the International Parkinson and Movement Disorder…