In this longitudinal observational study. recently published in the Journal of the American Geriatrics Society, the authors investigate the occurrence of delirium in hospitalised patients with COVID‐19 and explore its association with adverse outcomes
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Breaking newsResearch
Update Alert 2: Hydroxychloroquine or Chloroquine for the Treatment or Prophylaxis of COVID-19
September 1, 2020This report, recently published in Annals of Internal Medicine, represents the second update of a previously published living systematic review (Hernandez AV, Roman YM, Pasupuleti V, et al. Hydroxychloroquine or chloroquine for treatment or prophylaxis of COVID-19. -
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Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19. A Randomized Clinical Trial
September 1, 2020he objective of this randomised, open-label trial, recently published in JAMA, was to determine the efficacy of 5 or 10 days of remdesivir treatment compared with standard care on clinical status on day 11 after initiation of treatment in patients with moderate COVID-19 infection. -
Breaking newsResearch
Cerebral Micro-Structural Changes in COVID-19 Patients – An MRI-based 3-month Follow-up Study
September 1, 2020In this prospective study, the authors aimed to identify the existence of potential brain microstructural changes related to SARS-CoV-2 infection. -
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Guillain-Barré syndrome in SARS-CoV-2 infection: an instant systematic review of the first six months of pandemic
September 1, 2020The aim of this study, recently published in the Journal of Neurology, Neurosurgery and Psychiatry was, by a systematic review of the reported cases of GBS in SARS-CoV-2 infection, to clarify the clinical and electrophysiological phenotype, to discuss, on the basis of the available data, whether the disease mechanism could be parainfective or postinfective and to speculate on the possible pathogenesis. -
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Tocilizumab among patients with COVID-19 in the intensive care unit: a multicentre observational study
September 1, 2020In this multicentre retrospective observational cohort study recently published in Lancet Rheumatology, the authors investigate the association between tocilizumab exposure and hospital-related mortality among patients requiring intensive care unit (ICU) support for COVID-19. -
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Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2
September 1, 2020Rapid and accurate diagnostic tests are essential for controlling the ongoing Covid-19 pandemic. -
Breaking newsResearch
Effects of COVID-19 pandemic on acute ischemic stroke care – A single-centre retrospective analysis of medical collateral damage
September 1, 2020In this report from Budapest, Hungary, the authors compared several clinical features (including time parameters, rate of intravenous thrombolysis and endovascular therapies) of patients admitted to a university stroke-unit within a 2-month COVID-pandemic period (March and April of 2020) with an identical pre-COVID period of 2019. -
Breaking newsEAN NewsResearchCOVID-19
The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings
July 27, 2020In this study recently published in Brain, the authors collected detailed clinical and paraclinical data from patients with suspected COVID-19-related neurological disorders in whom the diagnosis of COVID-19 was confirmed through RNA PCR, or where the diagnosis was probable/possible according to World Health Organisation criteria. -
Breaking newsEAN NewsResearchCOVID-19
Persistent symptoms in patients after acute COVID-19
July 27, 2020In this research letter recently published in JAMA, the authors assessed persistent symptoms in patients who had been discharged from hospital after recovery from COVID-19. -
Anosmia, stroke, paralysis, cranial nerve deficits, encephalopathy, delirium, meningitis, and seizures are some of the neurological complications in patients with COVID-19.
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Breaking newsEAN NewsResearchCOVID-19
Cerebrovascular disease in patients with COVID-19: neuroimaging, histological and clinical description
July 27, 2020In this study, recently published in Brain, the authors present cerebrovascular disease case incidence in hospitalised patients with SARS-CoV-2 infection. -
Breaking newsEAN NewsCOVID-19Research
COVID-19 and decompressive hemicraniectomy for acute ischemic stroke
July 27, 2020In this paper, the authors retrospectively reviewed all COVID-19–positive patients admitted to the neuroscience intensive care unit for monitoring of malignant cerebral oedema -
Breaking newsEAN NewsResearchCOVID-19
Microvascular injury and hypoxic damage: emerging neuropathological signatures in COVID‐19
July 27, 2020In this paper recently published in Acta Neuropathologica, the authors report neuropathology of two COVID-19 patients. -
Breaking newsEAN NewsCOVID-19Research
Characteristics and outcomes in patients with COVID-19 and acute ischaemic stroke. The global COVID-19 stroke registry
July 27, 2020In this paper, the authors pooled all consecutive patients hospitalised with laboratory-confirmed COVID-19 and acute ischaemic stroke across 28 sites from 16 countries.