In this study the authors retrospectively analyzed motor symptoms of longitudinally followed PD patients (n = 264) and compared motor disease progression before and during the COVID-19 pandemic.
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Breaking newsCOVID-19Acute and chronic neurological disorders in COVID-19: potential mechanisms of disease
Review of literature regarding mechanisms of acute and chronic neurological disorders in association with COVID-19. -
Breaking newsCOVID-19
Interpretation of vaccine associated neurological adverse events: a methodological and historical review
In this review, the authors discuss contemporary methodologies employed to investigate possible associations between vaccination and adverse neurological outcomes and why determining causality can be challenging. -
This cohort study evaluates the COVID-19-related case fatality rate (CFR) of patients with pre-existing neurological diseases.
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Breaking newsCOVID-19
Neuropathological findings from COVID-19 patients with neurological symptoms argue against a direct brain invasion of SARS-CoV-2: A critical systematic review
In this article the authors performed a systematic literature review on neuropathological studies in COVID-19, including 438 patients from 45 articles published by April 22, 2021. -
Breaking newsCOVID-19Anti-CD20 therapies decrease humoral immune response to SARS-CoV-2 in patients with multiple sclerosis or neuromyelitis optica spectrum disorders
The objective of this study was to investigate the seroprevalence and the quantity of SARS-CoV-2 antibodies in a cohort of patients with MS or NMO-SD. Blood samples were collected in patients diagnosed with COVID-19. -
Breaking newsCOVID-19
The impact of the COVID-19 pandemic on dementia risk: Potential pathways to cognitive decline
This critical review highlights the injury pathways possible through SARS-CoV-2 infection that have the potential to increase and contribute to cognitive impairment and dementia. -
In this article the authors searched 3 databases (PubMed, MEDLINE, and CINAHL) with search terms COVID-19, novel coronavirus, stroke, and cerebrovascular accident.
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This review aims to provide a clinical practice-oriented approach to SARS-CoV-2 vaccination in MS in the era of the COVID-19 pandemic.
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Breaking newsCOVID-19
Acute disseminated encephalomyelitis and COVID-19: A systematic synthesis of worldwide cases
Acute disseminated encephalomyelitis (ADEM) has been reported after coronavirus disease 2019 (COVID-19). In this review, the authors systematically included worldwide reported cases on this association. -
Breaking newsCOVID-19
Neurological symptoms and complications in predominantly hospitalized COVID-19 patients – results of the European multinational LEOSS registry
In this study the authors analyzed COVID-19 patients of 127 centers, diagnosed between 01/2020 and 02/2021, and registered at the European multinational LEOSS registry ‘Lean European Open Survey on SARS-Infected Patients’. -
Breaking newsCOVID-19
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
In this article the authors detect auto-Abs neutralizing 100-fold lower, more physiological, concentrations of IFN-α and/or -ω in 13.6% of 3,595 patients with critical COVID-19, including 21% of 374 patients > 80 years, and 6.5% of 522 patients with severe COVID-19. -
Breaking newsCOVID-19
Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors
The authors of this article hypothesize that convalescent plasma has a higher efficacy, as defined by death within 30 days of transfusion, when the convalescent plasma donor and treated patient were in close geographic proximity. -
Breaking newsCOVID-19Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial
In this article the authors aimed to evaluate the efficacy of awake prone positioning to prevent intubation or death in patients with severe COVID-19 in a large-scale randomised trial. -
In this article the authors conducted a prospective cohort study involving patients with suspected VITT who presented to hospitals in the United Kingdom between March 22 and June 6, 2021.