Case series/case reports (Indigo)
The objective of this retrospective case series was to describe demographic, clinical, radiological and laboratory characteristics, as well as outcomes, of patients admitted for COVID-19 at Infanta Leonor University Hospital (ILUH) in Madrid, Spain. All patients attended at ILUH testing positive to reverse transcriptase-PCR on nasopharyngeal swabs and diagnosed with COVID-19 between 1 March 2020 and 28 May 2020 were included. A total of 1549 COVID-19 cases were included (median age 69 years (IQR 55.0-81.0), 57.5% men). 78.2% had at least one underlying comorbidity, and the most frequent was hypertension (55.8%). The most frequent symptoms at presentation were fever (75.3%), cough (65.7%) and dyspnoea (58.1%). 81 (5.8%) patients were admitted to the intensive care unit (ICU) (median age 62 years (IQR 51-71); 74.1% men; median length of stay 9 days (IQR 5-19)), and 82.7% of them needed invasive ventilation support. 1393 patients had an outcome recorded at the end of the study period (case fatality ratio: 21.2% (296/1393)).
Independent factors associated with fatality were (OR; 95% CI): age (1.07; 1.06 to 1.09), male sex (2.86; 1.85 to 4.50), neurological disease (1.93; 1.19 to 3.13), chronic kidney disease (2.83; 1.40 to 5.71) and neoplasia (4.29; 2.40 to 7.67). The percentage of hospital beds occupied with COVID-19 almost doubled (702/361), with the number of patients in ICU quadrupling its capacity (32/8). Median length of stay was 9 days (IQR 6-14). The authors concluded that this study provides clinical characteristics, complications and outcomes of patients with COVID-19 admitted to a European secondary hospital. Fatal outcomes were similar to those reported by hospitals with a higher level of complexity.
DOI: 10.1136/bmjopen-2020-042398
