In this issue of the Neuropenews, our Subspecialty Scientific Panel Sleep-wake disorders invites you to read an article on Alzheimer’s disease:
“Alzheimer’s disease (AD) is the most frequent dementia. Sporadic AD is thought to be due, in part, to impaired amyloid clearance. Amyloid clearance has been shown to be increased during the night.
The present paper relates amyloid clearance specifically to the deepest stage of sleep, i.e. slow wave sleep.”
- Mander BA, Marks SM, Vogel JW, et al. β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation. Nature Neuroscience 2015; 18: 1051-7.
Ulf Kallweit, MD
Senior Physician
Neurology Department
Bern University Hospital
Bern, Switzerland
Secretary, EAN Scientific Panel Sleep-Wake Disorders
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